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81.
Jung-Taek Kim Hyun-Ho Kim Jae-Hyung Kim Yoon-Ho Kwak Eui-Chan Chang Yong-Chan Ha 《The Journal of arthroplasty》2018,33(3):777-782
Background
Treatment of unstable intertrochanteric fracture in elderly patients remains challenging. The purpose of this prospective study is to determine clinical and radiological results of cementless bipolar hemiarthroplasty using a fully porous-coated stem in osteoporotic elderly patients with unstable intertrochanteric fractures with follow-up over 5 years.Methods
From January 2010 to December 2011, we performed 123 cementless bipolar hemiarthroplasties using fully porous-coated stem to treat unstable intertrochanteric fractures in elderly patients with osteoporosis. Clinical and radiographic evaluations were performed.Results
Fifty-three patients died and 14 patients were lost during the follow-up period. Mean follow-up period was 61.8 months postoperatively. Their mean Harris hip score was 77 points (range 36-100). None of these hips had loosening of the stem or osteolysis. Postoperative complications included nonunion of greater trochanter in 2 hips and dislocation in 2 hips. Two patients were reoperated due to periprosthetic fracture. One patient underwent implant revision due to periprosthetic infection. Thirty-one patients maintained walking activities similar to those before fracture. With follow-up period of 83 months, cumulative survival rates were 97.3% and 99.1% with reoperation for any reason and femoral stem revision as endpoint, respectively.Conclusion
Cementless bipolar hemiarthroplasty using a fully porous-coated stem is a useful surgical treatment option for unstable intertrochanteric fracture in elderly patients with osteoporosis. 相似文献82.
Richard J. van Arkel Shaaz Ghouse Piers E. Milner Jonathan R. T. Jeffers 《Journal of orthopaedic research》2018,36(5):1508-1518
Additive manufacturing offers exciting new possibilities for improving long‐term metallic implant fixation in bone through enabling open porous structures for bony ingrowth. The aim of this research was to investigate how the technology could also improve initial fixation, a precursor to successful long‐term fixation. A new barbed fixation mechanism, relying on flexible struts was proposed and manufactured as a push‐fit peg. The technology was optimized using a synthetic bone model and compared with conventional press‐fit peg controls tested over a range of interference fits. Optimum designs, achieving maximum pull‐out force, were subsequently tested in a cadaveric femoral condyle model. The barbed fixation surface provided more than double the pull‐out force for less than a third of the insertion force compared to the best performing conventional press‐fit peg (p < 0.001). Indeed, it provided screw‐strength pull out from a push‐fit device (1,124 ± 146 N). This step change in implant fixation potential offers new capabilities for low profile, minimally invasive implant design, while providing new options to simplify surgery, allowing for one‐piece push‐fit components with high levels of initial stability. © 2017 The Authors. Journal of Orthopaedic Research® Published by Wiley Periodicals, Inc. on behalf of the Orthopaedic Research Society. J Orthop Res 36:1508–1518, 2018. 相似文献
83.
LAWRENCE GOULD CHANDRAKANT PATEL WILLIAM BECKER 《Pacing and clinical electrophysiology : PACE》1986,9(6):1202-1205
Experience with 163 unipolar tined porous endocardial electrodes is reported. One patient required repositioning of the electrode because of exit block. There were no other complications in the entire series of patients. All of the patients had low chronic stimulation thresholds. The mean pulse width 24 hours after implantation was 0.0534 ± 0.0128 ms. Seventy-four patients were restudied six months after implantation. The mean pulse width threshold was then 0.07432 ± 0.0775 ms. Fifty-four patients were evaluated one year after lead implantation. The mean pulse width threshold was then 0.0611 ± 0.0230 ms. The pulse generator was reprogrammed to a lower pulse width in all of the patients. This permitted a substantial prolongation of the pulse generator life. The cost effectiveness of the pulse generator was also greatly improved by pacing with reduced pulse widths. In an additional 16 patients, the voltage amplitude was reduced from 5.0 volts to 2.5 volts. This permitted an even greater increase in the pulse generator longevity. 相似文献
84.
Effective Enzyme Coimmobilization and Synergistic Catalysis on Hierarchically Porous Inorganic/Organic Hybrid Microbeads Fabricated Via Droplet‐Based Microfluidics 下载免费PDF全文
In this paper, a novel and robust droplet‐based microfluidic method to fabricate poly(ε‐caprolactone)/silica (PCL/SiO2) hybrid microbeads with hierarchically porous architecture is described and their performance as multienzyme carriers for cascade catalysis is further investigated in detail. In addition to the precise control on size and monodispersity of PCL/SiO2 microbeads enabled by the microfluidic method, the presence of ammonia as a catalyst for the hydrolysis and condensation of tetraethylorthosilicate makes it possible to manipulate the competition between sol–gel process and solvent extraction and thus adjust the surface porosity of hybrid microbeads, which eliminates the use of porogens/templates and also the complicated post‐treatment. Isothiocyanate‐immunoglobulin G/cyanine 3‐bovine serum albumin (FITC‐IgG/Cy3‐BSA) and superoxide dismutase/chloramphenicol acetyltransferase (SOD/CAT) are coimmobilized, respectively onto hierarchically porous PCL/SiO2 hybrid microbeads via either physical adsorption or covalent binding. Fluorescence intensity of coimmobilized FITC‐IgG/Cy3‐BSA proves that the proteins/enzymes immobilization amount via covalent binding is much higher than physical adsorption. The enhanced enzymatic activity, total antioxidant capacity, and reusability assay reveal that coimmobilized SOD/CAT exhibits better performance compared with the mono‐immobilized ones, mainly due to their mutual synergistic effect. The excellent results achieved in the work indicate that hierarchically porous PCL/SiO2 hybrid microbeads are very promising carriers for multienzymatic catalysis. 相似文献
85.
新生儿科实施整体护理的对比分析 总被引:6,自引:1,他引:6
整体护理是以现代护理观为指导,以护理程序为框架,根据病人身心、社会文化需要而提供的优质护理。为适应现代护理发展需要,作为护理人员必须转变观念,将过去以“疾病为中心”的功能制护理转为以“病人为中心”的整体护理,以提高护理质量,降低护理并发症,为此,我们根据新生儿专科特 相似文献
86.
R. Michael Meneghini Christopher Meyer Christine A. Buckley Arlen D. Hanssen David G. Lewallen 《The Journal of arthroplasty》2010
Highly porous metal acetabular components have emerged for revision hip arthroplasty. However, superior mechanical stability over traditional cementless components has not been demonstrated. Three different cementless acetabular components, including 2 highly porous tantalum designs, were inserted into hemipelvis specimens with a superolateral defect. Mechanical testing was performed to failure using a servohydraulic testing machine. The porous tantalum designs exhibited superior stability over the traditional cementless implant (P < .05). There was no difference in mechanical stability between the rigid modular tantalum shell and the more flexible revision tantalum shell (P > .46). In acetabular revision, highly porous tantalum acetabular components provide superior mechanical stability. However, these results suggest that improved frictional resistance is a more important design feature over implant flexibility with this particular implant. 相似文献
87.
目的:研究静态与动态加载下仿生型种植体骨界面应力分布状况和疲劳行为,为研发能有效地转移应力至周围骨组织的新型种植体提供理论依据。方法:采用CAD(Pro/E Widefire 2.0)软件建立颌骨和钛种植体的三维有限元模型,设置全致密型(1号)和仿生型(2号)两种结构钛种植体,采用Ansys Workbench 10.0软件分析静态与动态加载下种植体骨界面应力分布状况,并对2号种植体进行疲劳行为分析。结果:在相同载荷下,1号和2号种植体在皮质骨区均为高应力区,2号种植体界面最大应力值、高应力区域面积、根端区最大应力值均低于1号种植体,从上至下种植体骨界面应力呈均匀递减趋势。动态加载的界面应力比静态的界面应力高17.15%。两种加载方式下,两种种植体在皮质骨区界面最大应力值无差别;在松质骨区, 1号的界面最大应力值比2号高75.97%;在根端区,1号的界面最大应力值比2号高22.46%,种植体界面最大应力远小于纯钛的屈服强度。2号种植体颈部皮质骨边缘的最大应力值比1号高7.85%,皮质骨边缘的最大应力值未达到皮质骨的屈服强度。预载50~300 N动态载荷,致密芯的安全系数均在10以上,随载荷加大,多孔层的界面应力呈线性增加,动态加载轴向300 N 和颊舌向45°25 N时,多孔层界面最大应力为11.38 MPa。结论:仿生型种植体有利于松质骨区及根端区界面应力转移到周围骨组织,其几何结构设计能耐受正常咀嚼的疲劳载荷,是安全的设计。 相似文献
88.
Biologic ingrowth can be difficult to achieve in acetabular component revision, especially in cases with significant bone loss. The purpose of this study was to review our clinical results of acetabular component revisions in patients with significant bone loss using a porous tantalum biomaterial. This is a retrospective review of 25 patients. There were 16 females and 9 males with a mean age of 71.7 ± 10.54 years. The mean follow up was 39 ± 11.09 months (range, 28-55 months). All patients in this series had combined segmental and cavitary bone loss, Paprosky type 2 or type 3. Of 22 patients in this series, 21 had a well-fixed and functioning implant at latest follow up. All 21 patients developed ingrowth along the tantalum surface despite compromised host bone. There were no cases of dislocation or aseptic loosening. Porous tantalum appears to be a promising material for use in revision hip arthroplasty to facilitate biologic ingrowth in patients with acetabular bone loss. 相似文献
89.
90.